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If anaphylaxis or severe allergic reaction is suspected, the medication should be discontinued immediately
While these suggest a favorable profile at moderate doses, large-scale human clinical trials haven't been conducted
Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
Additionally, it has been demonstrated that HMGB1 may contribute to the pathogenesis of MASLD by promoting insulin resistance [226]
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